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Androstenedione

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Other names:

3-Andro Xtreme, Andro-Gen, Andro-Stack, Animal Stak, Nor Andro Ripped Fuel Stack

What it is supposed to do:

Help build muscle mass and recover quickly from injury.

How it is supposed to work:

Androstenedione is a potent anabolic steroid, produced in the adrenal gland and gonads. It is converted to testosterone by the liver. Testosterone is available by prescription only, whereas androstenedione can be purchased over the counter as a dietary supplement.

Toxic effects:

Same effects as testosterone:

Heart disease, heart attacks, blood pressure elevation;
Liver disease, cancer,
Testicular shrinkage, and irreversible breast enlargement; Development of male characteristics in women;
Growth stunting in adolescents;
Multiple skin effects including acne, oily hair & skin, cysts, abnormal growth of hair or loss of hair, stretch marks, dermatitis, and skin infections;
Decrease in strength of muscle-tendon unit resulting in a greater tendency for strains and rupture;
Aggressive behavior ("roid rage"), psychosis, mood changes, suicide.

Some of the  effects are irreversible.

Does it work?

Little is known about whether androstenedione works. One study showed no differences in muscle size, strength or overall body composition. Another study showed a transient increase in testosterone levels but no effects on athletic performance.

Other Information: 

Banned by the International Olympic Committee, National Football League, National Collegiate Athletic Association, and National Basketball Association

References:

  1. Koch, JJ. Performance-enhancing substances and their use among adolescent athletes. Pediatrics in Review. September 2002;23(9):310-7.
     
  2. Greydanus, DE and Patel, DR. Sports doping in the adolescent athlete: The hope, hype and hyperbole. Pediatric Clinics of North America. August 2002; 49(4):829-55.
     
  3. Congeni, J and Miller, S. Supplements and drugs used to enhance athletic performance. Pediatric Clinics of North America. April 2002; 49(2):435-61.
     
  4. Ahrendt, DM. Ergogenic aids: counseling the athlete. American Family Physician. March 2001;63(5):913-22.
     
  5. Blue, JG and Lombardo, JA. Nutritional aspects of exercise: Steroids and steroid-like compounds. Clinics in Sports Medicine. July 1999;18(3):667-687.
 

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Last modified: February 24, 2004