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Cranberry

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Other names:

Also known as Vaccinium macrocarpon.  Common products that contain this include: Cranberry Extract

What is it supposed to do?

Used to treat a urinary tract infection

How it is supposed to work:

The mechanism of action with cranberry is not completely understood.

Toxic effects: 

None found in the literature

Does it work?

In a recent study, a cranberry juice beverage did indeed reduce the frequency of both bacteriuria (the passage of bacteria in the urine) and pyuria (presence of pus, indicating white blood cells in the urine) in elderly women.

A recent study found that an extract of cranberry inhibited an enzyme associated with a reduction in cancer risk.

Other information:

Research has found that fructose, a common sugar in many fruit juices, had some anti-adherence effect on E. coli bacterium. They also found that a compound isolated from cranberry juice (and blueberry juice) had the most potent effect. The evolving theory is that this compound produces an antibacterial effect in the gut or the bladder by adhering to the tiny hairs of the bacterial surface, thus preventing the bacteria from implanting in the tissue mucosal linings, and simply flushing them out of the body via the urine.

References:

  1. Stapleton A. Novel approaches to prevention of urinary tract infections. Infect Dis Clin North Am 2003;17(2):457-471.
     
  2. Jepson RG. Cranberries for preventing urinary tract infections. Cochrane Database Syst Review 2001;CD001321.
     
  3. Stothers LA. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infections in women. Can J Urol 2002;9(3):1558-1562.
 

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Last modified: February 25, 2004